Xing1 animal documentation

Aging study: Electrocardiogram for 29 inbred strains of mice   (2008)

Xing S, Korstanje R, Paigen B
With: Schultz D, Godfrey D


Acclimation and testing periods

Vendor Mice were obtained from The Jackson Laboratory (JAX®, Bar Harbor, ME)
6, 12, 20 months
All mice were fed Lab diet® 5K52 (6% fat, PMI Nutritional International, Bentwood, MO) ad libitum
Drinking water was acidified to pH 2.8 to 3.2 to prevent bacterial growth
Same-sex mice were housed four per pen in duplex polycarbonate cages (31x31x214cm) equipped with pressurized individually ventilated mouse racks (Thoren Caging Systems Inc.) with HEPA filtered supply and exhaust
Steam autoclaved white pine shavings
12 hours (light) on, 12 hours off; or 12 h light : 12 h dark cycle
Relative humidity ~50%
21-23 °C
Health status
The Jackson Laboratory Diagnostics Laboratory routinely monitors and documents animal health status using statistically valid sampling procedures and standard protocols. (Sentinel animals are tested). Detailed health status reports for each animal room represented from this project are on file and available on request. See JAX Mice Quality Control Programs or the JAX Mice Catalog for the list of agents monitored.