Acclimation & testing periods
The Jackson Laboratory (JAX®, Bar Harbor, ME)
Ages Tested at 8-18 wks of age Feed
Standard chow (Purina Prolab RMH3000, 14 kcal% fat) until 8 wks of age; high-fat food given 8-18 wks of age, D09092903 (Research Diets, New Brunswick NJ, 45 kcal% fat), with or without olanzapine. All food given ad libitum throughout experiment.
Water Provided ad libitum Temperature 20-24°C Humidity 40-50% Housing Housed 4 per cage; standard 20 cm x 30 cm ventilated polysulfone cages with Bed-O-Cob bedding Photoperiod 14:10h light-dark cycle Care and Use
Protocols approved by the Institutional Animal Care and Use Committee of the University of North Carolina at Chapel Hill