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Examples
Phenotype measures associated with
ontology
term
MP:0013275 'abnormal xenobiotic metabolism'
List studies
MGI
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All measures in this list are mapped to the
ontology descendants
of MP:0013275. None are mapped to MP:0013275 directly.
MP:0012691 abnormal acetaminophen metabolism
MP:0012692 abnormal fluoxetine metabolism
MP:0012696 abnormal trichloroethene metabolism
This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.
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Data set
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Rusyn2
(2)
Rusyn6
(13)
Threadgill2
(6)
Wiltshire2
(1)
Procedure / Protocol
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drug and metaboli...
(22)
Treatment
Clear All
acetaminophen
(6)
fluoxetine
(1)
trichloroethylene
(15)
Panel
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inbred
(22)
Sex
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m
(22)
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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
Year
Rusyn2:67
Rusyn2
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (serum DCA x 10
-3
) [nmol/mL]
DCA_tce
36167
time after treatment: 2h 8h 24h
inbred
15
m
7wks
N=3
2010
Rusyn2:75
Rusyn2
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (serum TCA) [nmol/mL]
TCA_tce
36175
time after treatment: 2h 8h 24h
inbred
15
m
7wks
N=3
2010
Rusyn6:2
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (serum TCA) [nmol/mL]
TCA_serum_tce
51202
inbred
7
m
6-7wks
N=3
2014
Rusyn6:4
Rusyn6
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (serum DCA) [nmol/mL]
DCA_serum_tce
51204
inbred
7
m
6-7wks
N=3
2014
Rusyn6:6
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl) glutathione (serum DCVG) [pmol/mL]
DCVG_serum_tce
51206
inbred
4
m
6-7wks
N=2
2014
Rusyn6:8
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC) [pmol/mL]
DCVC_serum_tce
51208
inbred
7
m
6-7wks
N=3
2014
Rusyn6:16
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (liver TCA) [nmol/g]
TCA_liver_tce
51216
inbred
7
m
6-7wks
N=4
2014
Rusyn6:18
Rusyn6
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (liver DCA) [nmol/g]
DCA_liver_tce
51218
inbred
7
m
6-7wks
N=4
2014
Rusyn6:20
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroethanol (liver TCOH) [nmol/g]
TCOH_liver_tce
51220
inbred
7
m
6-7wks
N=4
2014
Rusyn6:22
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl) glutathione (liver DCVG) [pmol/g]
DCVG_liver_tce
51222
inbred
7
m
6-7wks
N=4
2014
Rusyn6:58
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (kidney TCA) [nmol/g]
TCA_kidney_tce
51258
inbred
7
m
6-7wks
N=4
2014
Rusyn6:60
Rusyn6
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (kidney DCA) [nmol/g]
DCA_kidney_tce
51260
inbred
6
m
6-7wks
N=3
2014
Rusyn6:62
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroethanol (kidney TCOH) [nmol/g]
TCOH_kidney_tce
51262
inbred
7
m
6-7wks
N=4
2014
Rusyn6:64
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g]
DCVG_kidney_tce
51264
inbred
6
m
6-7wks
N=2
2014
Rusyn6:66
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g]
DCVC_kidney_tce
51266
inbred
6
m
6-7wks
N=2
2014
Threadgill2:9
Threadgill2
drug and metabolite quantification
acetaminophen
serum acetaminophen (APAP), 50 mg/mL dose acetaminophen [µg/mL]
APAP50
39609
baseline 0.5h 1h 2h 3h 6h
inbred
5
m
6-8wks
N=5
2005
Threadgill2:16
Threadgill2
drug and metabolite quantification
acetaminophen
serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen [µg/mL]
APAP_Sulf_50
39616
baseline 0.5h 1h 2h 3h 6h
inbred
5
m
6-8wks
N=5
2005
Threadgill2:22
Threadgill2
drug and metabolite quantification
acetaminophen
serum acetaminophen glucuronide (APAP-Glc), 50 mg/mL dose acetaminophen [µg/mL]
APAP_Glc_50
39622
baseline 0.5h 1h 2h 3h 6h
inbred
5
m
6-8wks
N=4
2005
Threadgill2:32
Threadgill2
drug and metabolite quantification
acetaminophen
serum acetaminophen (APAP), 300 mg/mL dose acetaminophen [µg/mL]
APAP300
39632
baseline 0.5h 1h 2h 3h 6h
inbred
5
m
6-8wks
N=5
2005
Threadgill2:38
Threadgill2
drug and metabolite quantification
acetaminophen
serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen [µg/mL]
APAP_Sulf_300
39638
baseline 0.5h 1h 2h 3h 6h
inbred
5
m
6-8wks
N=5
2005
Threadgill2:39
Threadgill2
drug and metabolite quantification
acetaminophen
serum acetaminophen glucuronide (APAP-Glc), 300 mg/mL dose acetaminophen [µg/mL]
APAP_Glc_300
39639
baseline 0.5h 1h 2h 3h 6h
inbred
5
m
6-8wks
N=5
2005
Wiltshire2:7
Wiltshire2
drug and metabolite quantification
fluoxetine
drug and metabolite concentration [ng/mL]
fluoxetine
38007
fluoxetine norfluoxetine
inbred
30
m
10-11wks
N=11
2011
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